SCHEMBL14723705

SCHEMBL14723705

CC[C@H](CCCCNC(=O)CNC(=O)OC(C)(C)C)NC(=O)CNC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ GAA P10253 1/20 0.47
▸ TDP1 Q9NUW8 4/20 0.46
▸ MAOA P21397 1/20 0.44
▸ MAOB P27338 1/20 0.44
▸ CA1 P00915 4/20 0.39
▸ CA2 P00918 4/20 0.39
▸ CA12 O43570 2/20 0.39
▸ CA9 Q16790 2/20 0.39
▸ SYK P43405 1/20 0.39
▸ CAPN1 P07384 1/20 0.39
▸ ATM Q13315 1/20 0.38
▸ TLR2 O60603 1/20 0.37
▸ TLR1 Q15399 1/20 0.37
▸ POLB P06746 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ CTSK P43235 3/20 0.36
▸ CTSS P25774 2/20 0.36
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16077485 1.00 MEN1 (0.47) MEN1KMT2AGAATDP1MAOA
SCHEMBL13741526 0.86 MEN1 (0.52) MEN1KMT2AGAATDP1MAOA
SCHEMBL14723706 0.81 TDP1 (0.66) MEN1KMT2AGAATDP1MAOA
SCHEMBL6244166 0.80 MEN1 (0.62) MEN1KMT2AGAATDP1MAOA
SCHEMBL9017485 0.80 TDP1 (0.56) MEN1KMT2AGAATDP1MAOA
SCHEMBL24096052 0.79 TDP1 (0.58) MEN1KMT2AGAATDP1MAOA
SCHEMBL7799440 0.78 SYK (0.44) MEN1KMT2AGAATDP1MAOA
SCHEMBL3311637 0.77 TDP1 (0.75) MEN1KMT2AGAATDP1MAOA
SCHEMBL16152420 0.77 CTSS (0.51) MEN1KMT2AGAATDP1MAOA
SCHEMBL22929002 0.76 TDP1 (0.78) MEN1KMT2AGAATDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS (AL), INC. 2017-07-20 — — US disclosed
US-20160303250-A1 Subcutaneous Delivery of Poly(oxazoline) Polymer Conjugates SERINA THERAPEUTICS (AL), INC. 2016-10-20 — — US disclosed
US-20140112880-A1 SUBCUTANEOUS DELIVERY OF POLY(OXAZOLINE) POLYMER CONJUGATES SERINA THERAPEUTICS, INC. (US) 2014-04-24 — — US disclosed
US-20130177521-A1 Subcutaneous Delivery of Poly(oxazoline) Conjugates SERINA THERAPEUTICS, INC. (US) 2013-07-11 — — US disclosed
US-8383093-B1 Subcutaneous delivery of poly(oxazoline) conjugates SERINA THERAPEUTICS, INC. (US) 2013-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130177521-A1 Subcutaneous Delivery of Poly(oxazoline) Conjugates OXA1L, PAICS, PAM MEN1 4043/4885KMT2A 686/4885GAA 303/4885
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP MEN1 2864/4885KMT2A 2735/4885GAA 229/4885
US-20140112880-A1 SUBCUTANEOUS DELIVERY OF POLY(OXAZOLINE) POLYMER CONJUGATES OXA1L, PAM, JMJD7 MEN1 4084/4885KMT2A 734/4885GAA 180/4885
US-20160303250-A1 Subcutaneous Delivery of Poly(oxazoline) Polymer Conjugates OXA1L, PAM, JMJD7 MEN1 4084/4885KMT2A 734/4885GAA 180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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