Hinokitiol

Hinokitiol

SCHEMBL1472387

CC(C)c1cccc(O)c(=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 8/20 1.00
HDAC8 Q9BY41 8/20 1.00
HDAC2 Q92769 6/20 1.00
ALOX12 P18054 3/20 1.00
TYR P14679 3/20 1.00
TP53 P04637 2/20 1.00
ALDH1A1 P00352 2/20 1.00
HTT P42858 2/20 1.00
KDM4E B2RXH2 1/20 1.00
MDM4 O15151 1/20 1.00
CA1 P00915 1/20 1.00
CA2 P00918 1/20 1.00
CYP3A4 P08684 1/20 1.00
MAPT P10636 1/20 1.00
HPGD P15428 1/20 1.00
ALOX15 P16050 1/20 1.00
CA5A P35218 1/20 1.00
MDM2 Q00987 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
CA9 Q16790 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hinokitiol SCHEMBL158795 0.83 TYR (0.71) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27551974 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27478967 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27478148 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27495432 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27551973 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27495431 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27476854 0.82 TYR (0.69) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27495430 0.77 HDAC4 (0.62) HDAC4HDAC8HDAC2ALOX12TYR
Hinokitiol SCHEMBL27478147 0.77 TYR (0.62) HDAC4HDAC8HDAC2ALOX12TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090966-A1 UROLITHIN COMPOSITIONS AMAZENTIS SA (CH) 2026-04-02 US claimed
EP-4687859-A2 DESMOPRESSIN ORAL COMPOSITIONS TULEX PHARMACEUTICALS, INC. (US) 2026-02-11 EP claimed
WO-2024211393-A2 DESMOPRESSIN ORAL COMPOSITIONS TULEX PHARMACEUTICALS INC. (US) 2024-10-10 WO claimed
US-20240329536-A1 COMPOSITION FOR REMOVING EDGE BEAD OF METAL-CONTAINING RESIST, AND METHOD FOR FORMING PATTERN COMPRISING STEP OF REMOVING EDGE BEAD BY USING SAME SAMSUNG SDI CO., LTD. (KR) 2024-10-03 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-4376802-A1 PERSONAL CARE COMPOSITION BASED ON AMINO ACID SURFACTANTS The Procter & Gamble Company (US) 2024-06-05 EP claimed
EP-4247321-A1 PERSONAL CARE COMPOSITIONS FREE OF SULFATED SURFACTANTS The Procter & Gamble Company (US) 2023-09-27 EP claimed
EP-1964544-B2 Sensitive skin perfumes TAKASAGO PERFUMERY CO LTD (JP) 2023-08-02 EP claimed
EP-3541355-B1 MALODOR COUNTERACTANT COMPOSITION AND METHODS BELL FLAVORS AND FRAGRANCES INC (US) 2023-06-07 EP claimed
US-20230120190-A1 ORAL COMPOSITION WITH SYNERGISTIC ASSOCIATION OF ORGANIC AND INORGANIC COMPONENTS FOR FULL MAINTENANCE OF ORAL HEALTH, PROCESS FOR OBTAINING AND USES THEREOF TEIXEIRA MARCELO RODRIGUES (BR) 2023-04-20 US claimed
EP-3235370-B2 WOOD FIBRE MAT FOR USE AS PLANT SUBSTRATE SWISS KRONO Tec AG (CH) 2022-06-01 EP claimed
WO-2022109094-A1 PERSONAL CARE COMPOSITIONS FREE OF SULFATED SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 2022-05-27 WO claimed
US-20220160606-A1 PERSONAL CARE COMPOSITION THE PROCTER & GAMBLE COMPANY 2022-05-26 US claimed
EP-2874664-B1 COMPOSITION FOR THERAPEUTIC USE, INCLUDING AN ORGANIC LIPID PHASE AND A RARE-EARTH RADIOISOTOPE COMPLEX CENTRE EUGENE MARQUIS (FR) 2019-06-19 EP claimed
EP-3349861-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE Henkel AG & Co. KGaA (DE) 2018-07-25 EP claimed
EP-1964544-B1 Sensitive skin perfumes TAKASAGO PERFUMERY CO LTD (JP) 2017-07-26 EP claimed
WO-2017046052-A1 PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE HENKEL AG & CO. KGAA (DE) 2017-03-23 WO claimed
EP-2110118-B1 Malodour reducing composition and uses thereof TAKASAGO PERFUMERY CO LTD (JP) 2014-11-19 EP claimed
EP-2110118-A1 Malodour reducing composition and uses thereof Takasago International Corporation (JP) 2009-10-21 EP claimed
US-20090257973-A1 MALODOR REDUCING COMPOSITION, FRAGRANCE COMPOSITION AND PRODUCT COMPRISING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090966-A1 UROLITHIN COMPOSITIONS UTS2R, TAS2R30, TAS2R42 HDAC4 1855/4885HDAC8 2797/4885HDAC2 874/4885
US-20220160606-A1 PERSONAL CARE COMPOSITION CUTA, AP3S1, POLR1C HDAC4 1502/4885HDAC8 2513/4885HDAC2 1428/4885
US-20090257973-A1 MALODOR REDUCING COMPOSITION, FRAGRANCE COMPOSITION AND PRODUCT COMPRISING THE SAME AKR1C4, AKR1C3, AKR1C1 HDAC4 1341/4885HDAC8 4048/4885HDAC2 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.