SCHEMBL14723952

SCHEMBL14723952

C#CCc1cc(CC)cc(CBr)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.33
PYCR1 P32322 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18640647 0.82 PTGS2 (0.44) PTGS2
SCHEMBL10069585 0.82 PTGS2 (0.44) PTGS2
SCHEMBL4756404 0.79 KDM4E (0.37) PTGS2
SCHEMBL28038072 0.76 PYCR1 (0.31) PYCR1
SCHEMBL26920214 0.72 TSHR (0.42) PYCR1
SCHEMBL4565961 0.71 PTGS2 (0.37) PTGS2
SCHEMBL2620706 0.71 PTGS2 (0.37) PTGS2
SCHEMBL13226845 0.71 PTGS2 (0.37) PTGS2
SCHEMBL11197732 0.71 PYCR1 (0.31) PYCR1
SCHEMBL11196340 0.70 TRPA1 (0.43) PYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8629266-B2 Dendritic starch-based dextrin adhesives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-01-14 US disclosed
US-20130116422-A1 DENDRITIC STARCH-BASED DEXTRIN ADHESIVES EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-05-09 US disclosed
US-8382889-B1 Dendritic starch-based dextrin adhesives EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130116422-A1 DENDRITIC STARCH-BASED DEXTRIN ADHESIVES CD14, STT3B, STT3A PTGS2 3969/4885PYCR1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.