SCHEMBL14725672

SCHEMBL14725672

Cn1cc2ccc3c(-c4cccc5c4oc4ccccc45)cc4cc5c(cc(-c6cccc7c6oc6ccccc67)c6ccc7cn(C)nc7c65)cc4c3c2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
PRKDC P78527 5/20 0.38
PIK3CD O00329 1/20 0.38
PIK3CB P42338 1/20 0.38
HDAC8 Q9BY41 1/20 0.34
ATM Q13315 1/20 0.33
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
POLB P06746 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
HRH4 Q9H3N8 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725669 0.83 SIRT2 (0.33) ALOX5MEN1KMT2APOLBKDM4E
SCHEMBL14725671 0.80 ALOX5 (0.52) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL14725633 0.76 ADORA3 (0.36) KMT2AKDM4EALDH1A1HPGDHSD17B10
SCHEMBL14725649 0.75 CYP11B2 (0.41)
SCHEMBL15497738 0.73 ALOX5 (0.55) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL16307763 0.73 ALOX5 (0.56) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL1005556 0.72 ALOX5 (0.59) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL16307756 0.72 ALOX5 (0.54) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL27058976 0.72 ALOX5 (0.54) ALOX5PRKDCPIK3CDPIK3CBHDAC8
SCHEMBL15446790 0.72 ALOX5 (0.52) ALOX5PRKDCPIK3CDPIK3CBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255084-B2 Heterocyclic compound and organic light-emitting device containing the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-02-09 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME TRPC1, TRPC4, TRPC6 ALOX5 648/4885PRKDC 4431/4885PIK3CD 1227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.