Sugi Predict

Sugi Predict / Compounds / SCHEMBL14729213

SCHEMBL14729213

SCHEMBL14729213

[N-]=[N+]=Nc1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.41
▸ CA2 P00918 3/20 0.41
▸ CA9 Q16790 3/20 0.41
▸ CA12 O43570 2/20 0.41
▸ CA7 P43166 2/20 0.41
▸ CA14 Q9ULX7 2/20 0.41
▸ LCK P06239 1/20 0.40
▸ FYN P06241 1/20 0.40
▸ TSHR P16473 3/20 0.40
▸ TP53 P04637 3/20 0.39
▸ TPMT P51580 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ CA5A P35218 2/20 0.39
▸ CA5B Q9Y2D0 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CA3 P07451 1/20 0.39
▸ SELL P14151 1/20 0.39
▸ HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21348607 0.95 CA1 (0.41) CA1CA2CA9CA12CA7
SCHEMBL28839209 0.88 CA12 (0.56) CA1CA2CA9CA12CA7
SCHEMBL16883316 0.83 TSHR (0.34) LCKFYNTSHRTP53MAPT
SCHEMBL13653935 0.82 MAOB (0.48) CA1CA2CA9CA12ALDH1A1
SCHEMBL29451102 0.82 CES2 (0.44) MAPT
SCHEMBL22834178 0.82 CES2 (0.44) MAPT
SCHEMBL16312302 0.82 CA1 (0.35) CA1CA2CA9CA12CA7
Hydrochloric Acid SCHEMBL28856154 0.81 MAOB (0.47) CA1CA2CA9CA12ALDH1A1
SCHEMBL22492181 0.80 HDAC1 (0.53) TSHRHDAC1HDAC2
SCHEMBL15397823 0.80 TP53 (0.38) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112444514-A Detection test paper based on metal-organic framework and preparation method thereof 江苏安泰安全技术有限公司 2021-03-05 — — CN claimed
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 — — US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 — — US disclosed
CN-116745020-A Gas production apparatus and gas production method 积水化学工业株式会社 2023-09-12 — — CN disclosed
US-10912836-B2 Synthetic antibody mimetic compounds (SyAMs) targeting cancer, especially prostate cancer YALE UNIVERSITY (US) 2021-02-09 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-10894807-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2021-01-19 — — US disclosed
WO-2020263703-A1 ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS STRATOS GENOMICS, INC. (US) 2020-12-30 — — WO disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
EP-2991677-B1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER UNIV YALE (US) 2020-07-15 — — EP disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
EP-2888312-B1 CROSS-LINKED ARAMID UNIV BURGOS (ES) 2016-08-10 — — EP disclosed
US-9328199-B2 Cross-linked aramid UNIVERSIDAD DE BURGOS (ES) 2016-05-03 — — US disclosed
US-20160082112-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-24 — — US disclosed
US-20150191570-A1 CROSS-LINKED ARAMID UNIVERSIDAD DE BURGOS (ES) 2015-07-09 — — US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10912836-B2 Synthetic antibody mimetic compounds (SyAMs) targeting cancer, especially prostate cancer CD47, FCGR1A, FCGR2A CA1 670/4885CA2 853/4885CA9 316/4885
US-10894807-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885
US-20160082112-A1 SYNTHETIC ANTIBODY MIMETIC COMPOUNDS (SYAMS) TARGETING CANCER, ESPECIALLY PROSTATE CANCER CD47, FCGR1A, FCGR2A CA1 485/4885CA2 774/4885CA9 321/4885
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO CA1 1688/4885CA2 1164/4885CA9 1034/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 CA1 3371/4885CA2 2607/4885CA9 2214/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 CA1 241/4885CA2 1257/4885CA9 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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