Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731298 | 0.90 | CHRNB2 (0.47) | CYP11B2ABCG2CYP11B1CYP17A1CHRNB2 | |
| SCHEMBL14731288 | 0.82 | CHRNB2 (0.45) | CYP11B2ABCG2CYP11B1CHRNB2CHRNA5 | |
| SCHEMBL14731283 | 0.81 | PDE5A (0.40) | CYP11B2ABCG2CYP11B1MAPK1KMT2A | |
| SCHEMBL16186207 | 0.78 | CYP11B2 (0.48) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL19204125 | 0.75 | CYP11B2 (0.47) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL17214442 | 0.75 | CYP11B2 (0.56) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL14474593 | 0.74 | CYP11B2 (0.49) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL16184298 | 0.73 | ABCG2 (0.51) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL17214443 | 0.70 | ABCG2 (0.56) | CYP11B2ABCG2CYP11B1CYP17A1GBA1 | |
| SCHEMBL16183299 | 0.69 | KCNA5 (0.57) | GBA1MAPK1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL COMPANY (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PPP3CB, PTPRG | CYP11B2 3834/4885ABCG2 2822/4885CYP11B1 3667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.