SCHEMBL14733730

SCHEMBL14733730

Cc1ccccc1N1C=CC[C@H]1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ADRB1 P08588 1/20 0.38
▸ ALOX5 P09917 2/20 0.38
▸ MAPT P10636 3/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MGLL Q99685 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ DDB1 Q16531 1/20 0.33
▸ CRBN Q96SW2 1/20 0.33
▸ SLC18A3 Q16572 1/20 0.33
▸ AR P10275 2/20 0.33
▸ TSHR P16473 2/20 0.32
▸ ACHE P22303 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MCOLN3 Q8TDD5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12757491 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL23680805 0.75 MAPK1 (0.37) SMN1; SMN2ALDH1A1HPGDALOX5MAPT
SCHEMBL19725777 0.74 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL22753233 0.68 ADRB1 (0.47) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL9891021 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL12643066 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL11995094 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL19258231 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL16716079 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL17886085 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 — — US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 — — US disclosed
US-20160315273-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, AND DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-10-27 — — US disclosed
US-9437833-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2016-09-06 — — US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 — — US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 — — US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 — — US disclosed
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES PROLYNX LLC 2014-10-02 — — US disclosed
US-20140191227-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2014-07-10 — — US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160315273-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, LIGHTING DEVICE, AND DISPLAY DEVICE LAGE3, ELOVL1, ELP1 SMN1; SMN2 656/4885ALDH1A1 768/4885HPGD 3774/4885
US-20140296476-A1 PRODRUGS AND DRUG-MACROMOLECULE CONJUGATES HAVING CONTROLLED DRUG RELEASE RATES ABCB1, ABCB11, DNPEP SMN1; SMN2 1727/4885ALDH1A1 701/4885HPGD 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback