SCHEMBL12757491

SCHEMBL12757491

Cc1ccccc1N1C=CC[C@@H]1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ADRB1 P08588 1/20 0.38
▸ ALOX5 P09917 2/20 0.38
▸ MAPT P10636 3/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MGLL Q99685 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ DDB1 Q16531 1/20 0.33
▸ CRBN Q96SW2 1/20 0.33
▸ SLC18A3 Q16572 1/20 0.33
▸ AR P10275 2/20 0.33
▸ TSHR P16473 2/20 0.32
▸ ACHE P22303 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MCOLN3 Q8TDD5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14733730 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL23680805 0.75 MAPK1 (0.37) SMN1; SMN2ALDH1A1HPGDALOX5MAPT
SCHEMBL19725777 0.74 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL22753233 0.68 ADRB1 (0.47) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL9891021 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL12643066 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL11995094 0.68 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1HPGDADRB1MAPT
SCHEMBL19258231 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL16716079 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5
SCHEMBL17886085 0.68 ALDH1A1 (0.38) SMN1; SMN2ALDH1A1HPGDADRB1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-9935276-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-03 — — US disclosed
US-20170365801-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-12-21 — — US disclosed
US-9735377-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 — — US disclosed
US-9673406-B2 Metal complexes with boron-nitrogen heterocycle containing ligands UNIVERSAL DISPLAY CORPORATION (US) 2017-06-06 — — US disclosed
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION 2017-04-20 — — US disclosed
US-20160293853-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-10-06 — — US disclosed
US-20160233429-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2016-08-11 — — US disclosed
US-20140231756-A1 PHOSPHORESCENT COMPOUND WITH FUSED RNG SUBSTITUTION UNIVERSAL DISPLAY CORPORATION (US) 2014-08-21 — — US disclosed
US-20140042413-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2014-02-13 — — US disclosed
US-20140039192-A1 METAL COMPLEXES WITH BORON-NITROGEN HETEROCYCLE CONTAINING LIGANDS UNIVERSAL DISPLAY CORPORATION (US) 2014-02-06 — — US disclosed
US-8586204-B2 Phosphorescent emitters and host materials with improved stability UNIVERSAL DISPLAY CORPORATION (US) 2013-11-19 — — US disclosed
US-8586203-B2 Metal complexes with boron-nitrogen heterocycle containing ligands UNIVERSAL DISPLAY CORPORATION (US) 2013-11-19 — — US disclosed
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2011-03-10 — — US disclosed
US-20100295032-A1 METAL COMPLEXES WITH BORON-NITROGEN HETEROCYCLE CONTAINING LIGANDS UNIVERSAL DISPLAY CORPORATION (US) 2010-11-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170365801-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, CTCF, RAP1A SMN1; SMN2 2636/4885ALDH1A1 726/4885HPGD 4350/4885
US-20110057559-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY DDT, TPST2, NUDT1 SMN1; SMN2 1459/4885ALDH1A1 901/4885HPGD 3905/4885
US-20160293853-A1 Organic Electroluminescent Materials and Devices OCIAD1, OCIAD2, JUND SMN1; SMN2 3932/4885ALDH1A1 400/4885HPGD 752/4885
US-20160233429-A1 Organic Electroluminescent Materials and Devices NBAS, TBCB, SLC1A2 SMN1; SMN2 4180/4885ALDH1A1 1352/4885HPGD 1314/4885
US-20100295032-A1 METAL COMPLEXES WITH BORON-NITROGEN HETEROCYCLE CONTAINING LIGANDS TBCB, NBAS, NMBR SMN1; SMN2 3590/4885ALDH1A1 3957/4885HPGD 2865/4885
US-20230337517-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD2, OCIAD1 SMN1; SMN2 2384/4885ALDH1A1 1442/4885HPGD 2658/4885
US-20170110676-A1 PHOSPHORESCENT EMITTERS AND HOST MATERIALS WITH IMPROVED STABILITY NUDC, TEC, MAP1LC3C SMN1; SMN2 1484/4885ALDH1A1 1636/4885HPGD 4424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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