SCHEMBL14733830

SCHEMBL14733830

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2ccc3sc4ccccc4c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.40
PIM3 Q86V86 1/20 0.39
LIMK1 P53667 1/20 0.37
CYP1A2 P05177 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PTPN7 P35236 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN12 Q05209 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.35
TSPO P30536 1/20 0.34
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
ROCK1 Q13464 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14649092 1.00 GPR3 (0.40) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL14649033 0.97 L3MBTL1 (0.41) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL14649034 0.97 L3MBTL1 (0.41) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL23556699 0.97 KDM4E (0.41) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL20706754 0.97 KDM4E (0.41) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL25941224 0.96 L3MBTL1 (0.44) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL25941731 0.96 L3MBTL1 (0.44) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL21481440 0.96 L3MBTL1 (0.44) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL14212276 0.96 L3MBTL1 (0.44) GPR3PIM3LIMK1CYP1A2KDM4E
SCHEMBL24173617 0.96 GPR3 (0.41) GPR3PIM3LIMK1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361378-B2 Organic electroluminescent device NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-23 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9837625-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-12-05 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
US-9437833-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2016-09-06 US disclosed
US-9437833-B2 Organic electroluminescence element Konica Minolta, Inc. (JP) 2016-09-06 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-9260658-B2 Organic electroluminescence element, lighting device and display device Konica Minolta, Inc. (JP) 2016-02-16 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150325796-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-11-12 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20150053949-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-02-26 US disclosed
US-20140339529-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2014-11-20 US disclosed
US-20140191227-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2014-07-10 US disclosed
US-20140191227-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Konica Minolta, Inc. (JP) 2014-07-10 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed
US-20130049576-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10361378-B2 Organic electroluminescent device ELF3, DDT, LEF1 GPR3 3910/4885PIM3 550/4885LIMK1 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.