Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 9/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ITK | Q08881 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607846 | 0.92 | ABL1 (0.35) | GSK3BDYRK1AMETABL1 | |
| SCHEMBL210475 | 0.91 | MET (0.36) | GSK3BDYRK1AMETABL1CDK9 | |
| SCHEMBL210474 | 0.91 | MET (0.36) | GSK3BDYRK1AMETABL1CDK9 | |
| SCHEMBL210473 | 0.91 | MET (0.36) | GSK3BDYRK1AMETABL1CDK9 | |
| SCHEMBL14734322 | 0.90 | CARM1 (0.36) | ABL1 | |
| SCHEMBL14734306 | 0.88 | SCN9A (0.32) | GSK3BDYRK1ACDK9 | |
| SCHEMBL14734323 | 0.87 | SCN9A (0.32) | GSK3BDYRK1ACDK9 | |
| SCHEMBL2724403 | 0.86 | GSK3B (0.36) | GSK3BDYRK1AMETABL1CDK9 | |
| SCHEMBL211198 | 0.84 | MET (0.36) | GSK3BDYRK1AMETABL1CDK9 | |
| SCHEMBL211199 | 0.84 | MET (0.36) | GSK3BDYRK1AMETABL1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053348-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | GSK3B 776/4885DYRK1A 4356/4885MET 1850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.