Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11461527 | 0.85 | PLA2G4B (0.50) | ALDH1A1TSHR | |
| SCHEMBL14735749 | 0.84 | NPC1 (0.58) | HSD17B3ESR1ALDH1A1TDP1NPC1 | |
| SCHEMBL7646115 | 0.84 | L3MBTL1 (0.44) | HSD17B3ESR1ALDH1A1TSHRCHRM1 | |
| SCHEMBL7650212 | 0.84 | L3MBTL1 (0.44) | HSD17B3ESR1ALDH1A1TSHRCHRM1 | |
| SCHEMBL22778963 | 0.83 | ALDH1A1 (0.57) | HSD17B3ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL2126591 | 0.83 | LMNA (0.56) | ALDH1A1TDP1NPC1RAB9AMAPT | |
| SCHEMBL8218440 | 0.82 | L3MBTL1 (0.68) | ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL7646419 | 0.82 | HDAC3 (0.56) | ALDH1A1MAPTESR2 | |
| SCHEMBL841978 | 0.82 | ESR2 (0.50) | HSD17B3ESR1ALDH1A1TSHRCHRM1 | |
| SCHEMBL7646664 | 0.81 | HAO1 (0.46) | HSD17B3ESR1ALDH1A1TSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |