SCHEMBL841978

SCHEMBL841978

COCCOCCOCCOCCOCC(=O)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.50
ALDH1A1 P00352 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
HSD17B3 P37058 2/20 0.46
PTPN1 P18031 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ABL1 P00519 1/20 0.43
POLB P06746 1/20 0.43
ALPI P09923 1/20 0.43
GAA P10253 1/20 0.43
ALPG P10696 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4454647 0.83 MAPT (0.53) ALDH1A1NPC1RAB9AMAPTKDM4E
SCHEMBL842153 0.83 NPC1 (0.59) ALDH1A1NPC1RAB9AHSD17B3TDP1
SCHEMBL862846 0.82 HSD17B3 (0.58) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL4447937 0.81 MAPT (0.54) ALDH1A1NPC1RAB9AMAPTGAA
SCHEMBL863102 0.81 ESR2 (0.59) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL14735749 0.81 NPC1 (0.58) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL26036082 0.81 TAS1R3 (0.43) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL22778963 0.80 ALDH1A1 (0.57) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL9001430 0.79 ESR1 (0.64) ESR2ALDH1A1NPC1RAB9AMAPT
SCHEMBL28394787 0.78 HSD17B3 (0.62) ESR2ALDH1A1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1651163-B1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2015-03-04 EP disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
EP-1651163-A4 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LTD (IN) 2008-03-26 EP disclosed
US-7335751-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2008-02-26 US disclosed
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2006-07-27 US disclosed
EP-1651163-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME Nobex Corporation (US) 2006-05-03 EP disclosed
WO-2005016240-A2 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME NOBEX CORPORATION (US) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167234-A1 Aryl carbamate oligomers for hydroilyzable prodrugs and prodrugs comprising same ALK, OGFR, AOX1 ESR2 2778/4885ALDH1A1 469/4885NPC1 1654/4885
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME ALK, AOX1, OGFR ESR2 2881/4885ALDH1A1 539/4885NPC1 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.