Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736894 | 0.84 | LMNA (0.41) | DRD4 | |
| SCHEMBL2597852 | 0.84 | KLK7 (0.41) | — | |
| SCHEMBL18577112 | 0.75 | CHIT1 (0.48) | — | |
| SCHEMBL28692423 | 0.75 | CHIT1 (0.48) | — | |
| SCHEMBL16966497 | 0.74 | HCRTR1 (0.31) | — | |
| SCHEMBL26605561 | 0.73 | OPRD1 (0.36) | — | |
| SCHEMBL2597809 | 0.71 | KLK7 (0.42) | — | |
| SCHEMBL17005468 | 0.71 | PDK1 (0.35) | — | |
| SCHEMBL17005432 | 0.71 | PDK1 (0.30) | — | |
| SCHEMBL4961994 | 0.69 | SLC18A2 (0.55) | SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059830-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059830-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | PRCP, PREP, ENPEP | DRD4 4740/4885SLC18A2 4451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.