Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740737 | 0.68 | MEN1 (0.42) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL22572982 | 0.68 | L3MBTL1 (0.53) | MEN1KMT2AAPAF1L3MBTL1SMN1; SMN2 | |
| SCHEMBL25238211 | 0.68 | NPC1 (0.49) | MEN1KMT2AAPAF1NSD2NPC1 | |
| SCHEMBL6671580 | 0.68 | CYP3A4 (0.56) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL4855643 | 0.68 | RAB9A (0.58) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL9527520 | 0.68 | HTR7 (0.55) | HSD17B10SIGMAR1 | |
| SCHEMBL5549334 | 0.67 | MEN1 (0.68) | MEN1KMT2AAPAF1NSD2RAB9A | |
| SCHEMBL9530968 | 0.67 | DRD2 (0.52) | LMNAGAA | |
| SCHEMBL24559082 | 0.67 | SMN1; SMN2 (0.53) | MEN1KMT2AAPAF1NSD2SMN1; SMN2 | |
| SCHEMBL19409870 | 0.66 | MALT1 (0.69) | MEN1KMT2AAPAF1NSD2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670216-B2 | Cannabinoid-2 agonists | ALLERGAN, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-20150284400-A1 | CANNABINOID-2 AGONISTS | ALLERGAN, INC. | 2015-10-08 | — | — | US | disclosed |
| US-9062004-B2 | Cannabinoid-2 agonists | ALLERGAN, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20130059848-A1 | CANNABINOID-2 AGONISTS | ALLERGAN, INC (US) | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284400-A1 | CANNABINOID-2 AGONISTS | CNR2, CNR1, GPR18 | MEN1 2059/4885KMT2A 1443/4885APAF1 4656/4885 |
| US-20130059848-A1 | CANNABINOID-2 AGONISTS | CNR2, CNR1, GPR18 | MEN1 2186/4885KMT2A 1864/4885APAF1 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.