Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744278 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743076 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL2635582 | 0.82 | LMNA (0.51) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14742913 | 0.81 | RAB9A (0.49) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743698 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743694 | 0.80 | HSP90AA1 (0.39) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743714 | 0.79 | MAPT (0.56) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743107 | 0.79 | LMNA (0.49) | ALDH1A1MEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL14743980 | 0.79 | NPC1 (0.51) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL14743294 | 0.78 | POLB (0.55) | ALDH1A1MAPTMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |