Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744244 | 0.90 | MAPK8 (0.49) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL14744260 | 0.89 | SMN1; SMN2 (0.55) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL14743310 | 0.88 | MEN1 (0.52) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL14743578 | 0.87 | RORC (0.44) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL14744254 | 0.87 | POLB (0.49) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL14743078 | 0.86 | HTT (0.50) | POLBNPC1MEN1KMT2AMAPK8 | |
| SCHEMBL14743721 | 0.84 | ALDH1A1 (0.54) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14743545 | 0.84 | CHUK (0.46) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL14742913 | 0.83 | RAB9A (0.49) | RAB9AMEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL14743714 | 0.81 | MAPT (0.56) | POLBRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |