Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743590 | 0.88 | GPBAR1 (0.40) | GPBAR1KMT2AMEN1TSHRHSD17B10 | |
| SCHEMBL14743289 | 0.85 | ALDH1A1 (0.49) | RAB9AGPBAR1L3MBTL1HSD17B10NPC1 | |
| SCHEMBL14743988 | 0.85 | HTT (0.39) | RAB9AGPBAR1KMT2AMEN1NPC1 | |
| SCHEMBL14744024 | 0.84 | GPBAR1 (0.42) | GPBAR1MRGPRX4 | |
| SCHEMBL14743756 | 0.84 | GPBAR1 (0.46) | GPBAR1L3MBTL1KMT2A | |
| SCHEMBL14743624 | 0.82 | GPBAR1 (0.38) | GPBAR1L3MBTL1MRGPRX4HPGD | |
| SCHEMBL14743979 | 0.80 | TSHR (0.42) | RAB9AGPBAR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL14743807 | 0.77 | HPGDS (0.40) | RAB9AGPBAR1L3MBTL1MRGPRX4TSHR | |
| SCHEMBL14743489 | 0.74 | GAA (0.41) | RAB9AGPBAR1L3MBTL1KMT2ATSHR | |
| SCHEMBL14743613 | 0.73 | SENP1 (0.44) | RAB9AL3MBTL1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |