Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 16/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743979 | 0.90 | TSHR (0.42) | GPBAR1KMT2AACLYL3MBTL1 | |
| SCHEMBL14743289 | 0.88 | ALDH1A1 (0.49) | GPBAR1L3MBTL1 | |
| SCHEMBL14743723 | 0.87 | KDM4E (0.47) | GPBAR1KDM4EKMT2AGRM1ACLY | |
| SCHEMBL14744024 | 0.87 | GPBAR1 (0.42) | GPBAR1ACLY | |
| SCHEMBL14743988 | 0.85 | HTT (0.39) | GPBAR1KDM4EKMT2AACLY | |
| SCHEMBL14743641 | 0.84 | RAB9A (0.45) | GPBAR1KMT2AL3MBTL1 | |
| SCHEMBL14743624 | 0.81 | GPBAR1 (0.38) | GPBAR1KDM4EACLYL3MBTL1 | |
| SCHEMBL14743646 | 0.79 | TSHR (0.43) | KDM4EKMT2AACLYL3MBTL1 | |
| SCHEMBL14743081 | 0.78 | PYGL (0.42) | GPBAR1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL14743613 | 0.78 | SENP1 (0.44) | KDM4EKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |