Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 2/20 | 0.46 |
| ▸ | ICOSLG | O75144 | 2/20 | 0.46 |
| ▸ | ICOS | Q9Y6W8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743106 | 0.90 | KDM4E (0.53) | MAPK1HSD17B10SMN1; SMN2KDM4ELMNA | |
| SCHEMBL14742996 | 0.78 | KDM4E (0.49) | MAPK1MAPK10HSD17B10SMN1; SMN2KCNMA1 | |
| SCHEMBL14743107 | 0.78 | LMNA (0.49) | MAPK1MAPK10HSD17B10SMN1; SMN2KCNMA1 | |
| SCHEMBL14743739 | 0.73 | MEN1 (0.48) | MAPK1HSD17B10SMN1; SMN2KDM4ELMNA | |
| SCHEMBL14743884 | 0.72 | RAB9A (0.39) | SMN1; SMN2KDM4ELMNANPC1RAB9A | |
| SCHEMBL204144 | 0.70 | HSD17B10 (0.54) | MAPK1MAPK10HSD17B10KDM4ELMNA | |
| SCHEMBL417914 | 0.70 | SERPINE1 (0.64) | — | |
| SCHEMBL3610020 | 0.69 | KDM4C (0.55) | MAPK1MAPK10HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL14743672 | 0.69 | KCNMA1 (0.50) | MAPK1SMN1; SMN2KCNMA1CHUKICOSLG | |
| SCHEMBL20897514 | 0.69 | MAPK1 (0.56) | MAPK1MAPK10HSD17B10KCNMA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |