Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 5/20 | 0.45 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | JAK1 | P23458 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743883 | 0.78 | MAPK1 (0.46) | KDM4EMAPK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL10062329 | 0.74 | KDM4E (0.63) | KDM4EMAPK1LMNAPOLBKMT2A | |
| SCHEMBL14742998 | 0.71 | RAB9A (0.40) | KDM4EPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14743107 | 0.70 | LMNA (0.49) | KDM4EMAPK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL27193268 | 0.68 | KDM4E (0.76) | KDM4ELMNAPOLBSMN1; SMN2KMT2A | |
| SCHEMBL11617697 | 0.68 | MAPK1 (1.00) | KDM4EMAPK1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL14743106 | 0.67 | KDM4E (0.53) | KDM4EMAPK1LMNASMN1; SMN2KMT2A | |
| SCHEMBL14743884 | 0.66 | RAB9A (0.39) | KDM4ELMNAPOLBSMN1; SMN2KMT2A | |
| SCHEMBL1520032 | 0.66 | KCNMA1 (0.75) | KDM4EMAPK1LMNAPOLBSMN1; SMN2 | |
| Methyl Alcohol SCHEMBL28281305 | 0.65 | GAA (0.84) | KDM4EMAPK1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |