Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746497 | 0.81 | RECQL (0.41) | — | |
| SCHEMBL14744504 | 0.79 | S1PR1 (0.49) | GAAALDH1A1S1PR1MAPTHTT | |
| SCHEMBL14744240 | 0.79 | HSPB1 (0.47) | ALDH1A1MAPTHTTPOLBKMT2A | |
| SCHEMBL14746704 | 0.78 | LMNA (0.38) | MAPTLMNAHTTKMT2ANPSR1 | |
| SCHEMBL14746593 | 0.78 | HSD17B10 (0.45) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL14746841 | 0.77 | PTGS2 (0.50) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL14746807 | 0.76 | AKR1C3 (0.46) | SMN1; SMN2MAPTLMNAHTTPOLB | |
| SCHEMBL12952709 | 0.75 | GAA (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL12952929 | 0.75 | GAA (0.53) | GAAALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14746574 | 0.75 | HSD17B10 (0.45) | ALDH1A1SMN1; SMN2NPBWR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |