Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 6/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 6/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30320910 | 0.79 | RORC (0.50) | RORC | |
| SCHEMBL14744202 | 0.79 | RORC (0.50) | RORC | |
| SCHEMBL14746409 | 0.78 | RORC (0.40) | GRIA1CACNG8ACLYRORC | |
| SCHEMBL14746573 | 0.77 | CYP3A4 (0.46) | — | |
| SCHEMBL28536731 | 0.77 | ACLY (0.35) | GRIA1CACNG8ACLYRORCGRIN2B | |
| SCHEMBL14746790 | 0.77 | ALDH1A1 (0.38) | L3MBTL1 | |
| SCHEMBL31533736 | 0.76 | KIF11 (0.41) | GRIA1CACNG8GRIN2BPDK2 | |
| SCHEMBL31533735 | 0.75 | ALDH1A1 (0.35) | L3MBTL1 | |
| SCHEMBL14744191 | 0.75 | RORC (0.44) | RORC | |
| SCHEMBL14746825 | 0.75 | ACLY (0.41) | GRIA1CACNG8ACLYRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |