Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746825 | 0.82 | ACLY (0.41) | RORCACLYSLC22A12GRIA1CACNG8 | |
| SCHEMBL20943238 | 0.81 | RORC (0.56) | RORCCYP2C9CYP2C19 | |
| SCHEMBL28888504 | 0.79 | TSHR (0.46) | RORC | |
| SCHEMBL14744335 | 0.78 | GRIA1 (0.39) | RORCACLYGRIA1CACNG8 | |
| SCHEMBL12003017 | 0.73 | PNLIP (0.42) | RORCSLC22A12 | |
| SCHEMBL14746610 | 0.71 | RORC (0.53) | RORCSLC22A12CYP2C9CYP2C19 | |
| SCHEMBL28536731 | 0.68 | ACLY (0.35) | RORCACLYCYP2C9CYP2C19GRIA1 | |
| SCHEMBL29699525 | 0.67 | KMO (0.51) | ACLYGRIA1CACNG8 | |
| SCHEMBL26739581 | 0.66 | TSHR (0.46) | — | |
| SCHEMBL13105717 | 0.65 | EPHX2 (0.46) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |