SCHEMBL1474743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1475256	0.91	RAB9A (0.59)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL14470267	0.86	RAB9A (0.56)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL1476803	0.79	RAB9A (0.58)	HPGDRAB9ANPC1L3MBTL1MAPT
	SCHEMBL14948947	0.73	RAB9A (0.55)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL1476488	0.71	NPC1 (0.54)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL1313654	0.70	ALDH1A1 (0.58)	RAB9ANPC1ALDH1A1KMT2ALMNA
	SCHEMBL1474697	0.70	RAB9A (0.56)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL14946441	0.70	RAB9A (0.52)	HPGDRAB9ANPC1L3MBTL1CACNA1B
	SCHEMBL1477101	0.70	RAB9A (0.67)	HPGDRAB9ANPC1MAPTALDH1A1
	SCHEMBL15190208	0.69	HPGD (0.53)	HPGDRAB9ANPC1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.