SCHEMBL1476488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1476492	0.76	NPC1 (0.56)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL1476803	0.72	RAB9A (0.58)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL14948947	0.71	RAB9A (0.55)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL1475256	0.71	RAB9A (0.59)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL1474743	0.71	HPGD (0.64)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL14470267	0.69	RAB9A (0.56)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL1474697	0.69	RAB9A (0.56)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL14946441	0.68	RAB9A (0.52)	NPC1RAB9AL3MBTL1POLBMAPT
	SCHEMBL1475114	0.68	EPHX2 (0.54)	NPC1RAB9APOLBMAPTKMT2A
	SCHEMBL1474547	0.67	NOTUM (0.59)	NPC1RAB9AL3MBTL1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.