Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 13/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105774 | 0.91 | INSR (0.53) | INSRMEN1HTTKMT2ATP53 | |
| SCHEMBL14708621 | 0.89 | INSR (0.51) | INSRMEN1HTTKMT2ATP53 | |
| SCHEMBL14747441 | 0.71 | ALDH1A1 (0.40) | MEN1HTTKMT2ATP53TSHR | |
| SCHEMBL1105772 | 0.71 | INSR (0.52) | INSR | |
| Iodide SCHEMBL8390160 | 0.71 | INSR (0.98) | INSR | |
| Iodide SCHEMBL8390162 | 0.71 | INSR (0.98) | INSR | |
| SCHEMBL14706829 | 0.70 | LMNA (0.43) | INSRMEN1HTTKMT2ATP53 | |
| SCHEMBL14747446 | 0.69 | INSR (0.49) | INSRHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL14706830 | 0.67 | INSR (0.40) | INSRMEN1HTTKMT2ATSHR | |
| Iodide SCHEMBL8390009 | 0.66 | INSR (0.98) | INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |