SCHEMBL14706830

SCHEMBL14706830

CCCCCCN(CCCCCC)S(=O)(=O)c1ccc2c(c1)sc(C=Cc1cc3c4c(c1)CCCN4CCC3)[n+]2CCCCS(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ INSR P06213 8/20 0.40
▸ ALDH1A1 P00352 3/20 0.35
▸ LMNA P02545 3/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ TSHR P16473 1/20 0.35
▸ HTT P42858 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ VCAM1 P19320 1/20 0.32
▸ P4HB P07237 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ MCOLN3 Q8TDD5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105774 0.77 INSR (0.53) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL14747441 0.69 ALDH1A1 (0.40) ALDH1A1LMNASMN1; SMN2L3MBTL1TSHR
SCHEMBL14708621 0.68 INSR (0.51) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL26644390 0.68 KMT2A (0.35) ALDH1A1LMNAL3MBTL1MEN1POLB
SCHEMBL13171852 0.67 INSR (0.53) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL1105772 0.67 INSR (0.52) INSRP4HB
SCHEMBL14747678 0.67 INSR (0.54) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL14706832 0.66 SNCA (0.48) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL1105806 0.66 SNCA (0.48) INSRALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL14706829 0.66 LMNA (0.43) INSRALDH1A1LMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8759526-B2 Dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes—useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. (US) 2014-06-24 — — US disclosed
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2013-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130045480-A1 Novel dyes, composite dyes, and oligonucleotides or polynucleotides comprising such dyes - useful or detection or quantification of desirable target molecules ANXA5, DCLRE1B, ANXA4 INSR 2463/4885ALDH1A1 3717/4885LMNA 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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