Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747876 | 0.84 | SIGMAR1 (0.43) | SIGMAR1CYP3A4 | |
| SCHEMBL14747877 | 0.83 | HTR1A (0.56) | HTR1APPARGPPARASTAT3TUBB4A | |
| SCHEMBL14747862 | 0.82 | HTR1A (0.40) | HTR1APPARGPPARASTAT3SIGMAR1 | |
| SCHEMBL12020315 | 0.81 | SKP2 (0.53) | HTR1APPARGPPARATUBB4ATUBB | |
| SCHEMBL12961274 | 0.81 | SIGMAR1 (0.43) | HTR1APPARGSIGMAR1CYP3A4 | |
| SCHEMBL1911890 | 0.80 | SIGMAR1 (0.45) | STAT3SIGMAR1CYP3A4 | |
| SCHEMBL12856097 | 0.80 | HTR1A (0.44) | HTR1ASIGMAR1LTA4HTRPV1CYP1A2 | |
| SCHEMBL15760679 | 0.79 | TUBB4A (0.53) | PPARGPPARATUBB4ATUBBTUBA3C | |
| SCHEMBL21755693 | 0.79 | HTR1A (0.59) | HTR1APPARGPPARASTAT3TUBB4A | |
| Benzene SCHEMBL2920819 | 0.79 | PPARG (0.54) | PPARGPPARACYP1A2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275413-B1 | 2,4-di(phenylamino)-pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders | NOVARTIS AG (CH) | 2013-03-06 | — | — | EP | disclosed |