SCHEMBL1474889

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1476776	0.89	RAB9A (0.59)	RAB9ANPC1TP53LMNAMAPT
	SCHEMBL1475058	0.83	RAB9A (0.71)	RAB9ANPC1TP53LMNACYP1A2
	SCHEMBL1475156	0.81	KMT2A (0.72)	RAB9ANPC1LMNAMAPTKMT2A
	SCHEMBL1474912	0.80	SMN1; SMN2 (0.54)	RAB9ANPC1MAPTKMT2AMEN1
	SCHEMBL1178001	0.76	RAB9A (0.80)	RAB9ANPC1TP53LMNAMAPT
	SCHEMBL15190060	0.73	RAB9A (0.59)	RAB9ANPC1TP53LMNAMAPT
	SCHEMBL5345477	0.73	ROCK2 (0.67)	NPC1KMT2AMEN1SMN1; SMN2L3MBTL1
	SCHEMBL9130703	0.72	FES (0.81)	MAPTCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL29460250	0.72	FES (0.81)	MAPTCYP1A2CYP3A4CYP2C9CYP2C19
	SCHEMBL1474434	0.72	HTT (0.59)	RAB9AKMT2ASMN1; SMN2ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.