Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052067 | 0.84 | CA12 (0.39) | ENPP2LPAR1LPAR2 | |
| SCHEMBL17370182 | 0.84 | ZDHHC20 (0.39) | FABP3CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL15752144 | 0.80 | ENPP2 (0.32) | ENPP2LPAR1LPAR2 | |
| SCHEMBL25857265 | 0.74 | SMN1; SMN2 (0.46) | FABP3CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL13978764 | 0.74 | BBOX1 (0.44) | FABP3CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL328730 | 0.74 | TSHR (0.41) | ENPP2LPAR1LPAR2TSHR | |
| SCHEMBL284261 | 0.74 | TSHR (0.41) | ENPP2LPAR1LPAR2TSHR | |
| SCHEMBL27999363 | 0.73 | HPGD (0.38) | MAPK1SMN1; SMN2TSHRGAARAB9A | |
| SCHEMBL16638188 | 0.73 | CHRM5 (0.42) | FABP3CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL65991 | 0.72 | FABP3 (0.39) | FABP3CHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751123-B1 | BIOCOMPATIBLE MATERIAL | VERTELLUS HOLDINGS LLC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-9006305-B2 | Biocompatible material | VERTELLUS SPECIALTIES INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-8980956-B2 | Methods for producing biocompatible materials | VERTELLUS SPECIALITIES INC. (US) | 2015-03-17 | — | — | US | disclosed |
| WO-2013033553-A1 | METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS | VERTELLUS SPECIALTIES INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013033554-A1 | BIOCOMPATIBLE MATERIAL | VERTELLUS SPECIALTIES INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| US-20130059926-A1 | METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS | VERTELLUS HOLDINGS, LLC | 2013-03-07 | — | — | US | disclosed |
| US-20130059970-A1 | BIOCOMPATIBLE MATERIAL | VERTELLUS HOLDINGS, LLC | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059970-A1 | BIOCOMPATIBLE MATERIAL | VCL, ITGAM, MACF1 | FABP3 3485/4885CHRM5 3319/4885CHRM1 1372/4885 |
| US-20130059926-A1 | METHODS FOR PRODUCING BIOCOMPATIBLE MATERIALS | VCL, ECPAS, MACF1 | FABP3 2001/4885CHRM5 1752/4885CHRM1 319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.