Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10151083 | 0.87 | HCAR3 (0.34) | HCAR3RORCCYP3A4ALDH1A1KDM4E | |
| SCHEMBL15075881 | 0.79 | HCAR3 (0.32) | HCAR3TYMS | |
| SCHEMBL19130780 | 0.74 | HCAR3 (0.59) | HCAR3ALDH1A1GAAMAPTHTT | |
| SCHEMBL9984014 | 0.70 | CYP3A4 (0.47) | CYP3A4LATS1LATS2ALDH1A1GAA | |
| SCHEMBL9408668 | 0.70 | CYP3A4 (0.38) | HCAR3CYP3A4LATS1LATS2ALDH1A1 | |
| SCHEMBL5716046 | 0.69 | CYP3A4 (0.46) | CYP3A4LATS1LATS2ALDH1A1KDM4E | |
| SCHEMBL18509336 | 0.68 | CYP3A4 (0.38) | CYP3A4LATS1LATS2ALDH1A1MAPT | |
| SCHEMBL23555163 | 0.66 | CCR5 (0.39) | CYP3A4ALDH1A1GAA | |
| SCHEMBL6832796 | 0.66 | ALDH1A1 (0.44) | CYP3A4ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL18175188 | 0.65 | CYP3A4 (0.37) | CYP3A4LATS1LATS2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | HYDRA BIOSCIENCES, INC. | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059869-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | HCAR3 332/4885RORC 1150/4885CYP3A4 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.