Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL15920702 | 0.97 | CA2 (0.44) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL2399806 | 0.78 | CA2 (0.50) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL45942 | 0.76 | CA2 (0.69) | CA2CYP2A6ALDH1A1CA12CA3 | |
| Water SCHEMBL28189314 | 0.76 | CA2 (0.69) | CA2CYP2A6ALDH1A1CA12CA3 | |
| Water SCHEMBL28254092 | 0.76 | CA2 (0.69) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL2503454 | 0.76 | CA2 (0.69) | CA2CYP2A6ALDH1A1CA12CA3 | |
| Fluoride SCHEMBL28187921 | 0.73 | CA2 (0.65) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL27949151 | 0.73 | CA2 (0.65) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL28829194 | 0.73 | CA2 (0.65) | CA2CYP2A6ALDH1A1CA12CA3 | |
| SCHEMBL28212763 | 0.73 | CA2 (0.65) | CA2CYP2A6ALDH1A1CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169607-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-06-02 | — | — | US | disclosed |
| US-20210275514-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | HOFFMANN LA ROCHE (US) | 2021-09-09 | — | — | US | disclosed |
| EP-3826679-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | F. Hoffmann-La Roche AG (CH) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020205765-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2020-10-08 | — | — | WO | disclosed |
| US-20200085810-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | HOFFMANN-LA ROCHE INC. | 2020-03-19 | — | — | US | disclosed |
| WO-2020021097-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-01-30 | — | — | WO | disclosed |
| EP-2755953-A1 | 3 -PYRIDINE CARBOXYLIC ACID HYDRAZIDES AS HDL-CHOLESTEROL RAISING AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-07-23 | — | — | EP | disclosed |
| US-8648099-B2 | 3-pyridine carboxylic acid hydrazides | HOFFMANN-LA ROCHE INC. (US) | 2014-02-11 | — | — | US | disclosed |
| WO-2013037703-A1 | 3 -PYRIDINE CARBOXYLIC ACID HYDRAZIDES AS HDL-CHOLESTEROL RAISING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-21 | — | — | WO | disclosed |
| US-20130065876-A1 | 3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065876-A1 | 3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES | HMGCR, HCAR3, HCAR1 | CA2 688/4885CYP2A6 269/4885ALDH1A1 172/4885 |
| US-20220169607-A1 | CARBAZOLE AND ACRIDINE PHOTOREDOX CATALYSTS FOR SMALL MOLECULE AND MACROMOLECULAR TRANSFORMATIONS | PCNA, PPOX, PARP1 | CA2 3220/4885CYP2A6 3241/4885ALDH1A1 1668/4885 |
| US-20210275514-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | GLS, ATP6V1B1, PLAAT2 | CA2 3715/4885CYP2A6 2367/4885ALDH1A1 2705/4885 |
| US-20200085810-A1 | COMPOUNDS FOR USE IN TREATING KIDNEY DISORDERS | GLS, ATP6V1B1, PLAAT2 | CA2 3715/4885CYP2A6 2367/4885ALDH1A1 2705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.