SCHEMBL1476492

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15190389	0.82	ALDH1A1 (0.58)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1474842	0.82	ALDH1A1 (0.81)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1475114	0.80	EPHX2 (0.54)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1474858	0.78	EPHX2 (0.52)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1474947	0.77	ALDH1A1 (0.57)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1476488	0.76	NPC1 (0.54)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1178320	0.73	ALDH1A1 (0.82)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL15190045	0.73	ALDH1A1 (0.70)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1474584	0.72	EPHX2 (0.51)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A
	SCHEMBL1474586	0.72	EPHX2 (0.51)	NPC1RAB9AALDH1A1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.