Propene

Propene

SCHEMBL14765283

C=CC.O.[MgH2]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Propene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propene SCHEMBL671855 0.94
Propene SCHEMBL768893 0.94
Propene SCHEMBL327436 0.94
Propene SCHEMBL27447062 0.94
Propene SCHEMBL11195626 0.88
Propene SCHEMBL14786292 0.88
Propene SCHEMBL28605748 0.88
Propene SCHEMBL3366466 0.88
Propene SCHEMBL22660951 0.88 ALDH1A1 (0.31)
Propene SCHEMBL10948784 0.88 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698600-B Preparation method and application of bulk flame-retardant polypropylene graft 湖南工学院 2022-09-27 CN disclosed
CN-109810404-B Polypropylene/metal hydroxide/rare earth compound flame-retardant material 浙江大学宁波理工学院 2021-11-23 CN disclosed
CN-110698600-A Preparation method and application of bulk flame-retardant polypropylene graft 湖南工学院 2020-01-17 CN disclosed
CN-109810404-A A kind of polypropylene/metal hydroxides/rare earth compound fire proofing 浙江大学宁波理工学院 2019-05-28 CN disclosed
CN-104629187-B A kind of multi-functional PP composite material and preparation method thereof 北京化工大学 2018-02-13 CN disclosed
CN-104080849-B Nanoclays Containing Flame Retardant Chemicals for Flame Retardant Applications 南图清洁科技股份公司 2016-08-31 CN disclosed
US-20160075862-A1 NANOCLAYS CONTAINING FLAME RETARDANT CHEMICALS FOR FIRE RETARDANT APPLICATIONS NANTO CLEANTECH S P A (IT) 2016-03-17 US disclosed
US-9193911-B2 Nanoclays containing flame retardant chemicals for fire retardant applications NANTO CLEANTECH S.P.A. (IT) 2015-11-24 US disclosed
CN-104629187-A Multifunctional polypropylene composite material and preparation method thereof UNIV BEIJING CHEMICAL 2015-05-20 CN disclosed
US-20140303295-A1 NANOCLAYS CONTAINING FLAME RETARDANT CHEMICALS FOR FIRE RETARDANT APPLICATIONS NANTO CLEANTECH S.P.A. (IT) 2014-10-09 US disclosed
CN-104080849-A Nanoclays Containing Flame Retardant Chemicals for Flame Retardant Applications NANTO PROTECTIVE COATING S R L 2014-10-01 CN disclosed
WO-2013034954-A1 NANOCLAYS CONTAINING FLAME RETARDANT CHEMICALS FOR FIRE RETARDANT APPLICATIONS NANTO PROTECTIVE COATING S.R.L. (IT) 2013-03-14 WO disclosed
CN-102675739-A Preparation method of halogen-free flame-retardant toughening polypropylene composite material UNIV JIAOTONG SOUTHWEST 2012-09-19 CN disclosed
CN-101151271-A Process for producing titanium alkoxide complex SUMITOMO CHEMICAL CO (JP) 2008-03-26 CN disclosed