Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12606931 | 0.89 | SLC6A1 (0.48) | FAAHITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL3059912 | 0.88 | GNAI3 (0.44) | FAAHITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL10811442 | 0.85 | — | — | |
| SCHEMBL27865199 | 0.83 | FAAH (0.43) | FAAHITGB3ITGA2BTPSAB1TPSD1 | |
| Sulfuric Acid SCHEMBL11698465 | 0.82 | GABRA5 (0.42) | FAAHITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL20481261 | 0.82 | SLC6A1 (0.46) | FAAHITGB3ITGA2BGNAO1GNAI3 | |
| SCHEMBL14860802 | 0.82 | SLC6A1 (0.46) | FAAHITGB3ITGA2BGNAO1GNAI3 | |
| SCHEMBL20481265 | 0.82 | SLC6A1 (0.46) | FAAHITGB3ITGA2BGNAO1GNAI3 | |
| SCHEMBL381083 | 0.82 | ITGB3 (0.66) | FAAHITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL2543926 | 0.82 | FAAH (0.49) | FAAHITGB3ITGA2BTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558578-B1 | NOVEL ALKYNE COMPOUNDS HAVING AN MCH ANTAGONISTIC EFFECT AND MEDICAMENTS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2013-03-13 | — | — | EP | disclosed |