Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | GOT1 | P17174 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.52 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146748 | 1.00 | KDM4E (0.52) | KDM4ELMNANPC1RAB9AGOT1 | |
| Hydrochloric Acid SCHEMBL3440483 | 0.98 | KDM4E (0.53) | KDM4ELMNANPC1RAB9AGOT1 | |
| Sulfuric Acid SCHEMBL3440665 | 0.89 | ALDH1A1 (0.43) | KDM4ELMNANPC1RAB9AGOT1 | |
| Sulfuric Acid SCHEMBL3440667 | 0.84 | EGFR (0.43) | KDM4ELMNANPC1RAB9AGOT1 | |
| SCHEMBL30944647 | 0.77 | KDM4E (0.52) | KDM4ELMNANPC1RAB9AGOT1 | |
| SCHEMBL15835530 | 0.77 | KDM4E (0.52) | KDM4ELMNANPC1RAB9AGOT1 | |
| SCHEMBL30523852 | 0.76 | KDM4E (0.55) | KDM4ELMNANPC1RAB9AGOT1 | |
| SCHEMBL1673296 | 0.76 | KDM4E (0.55) | KDM4ELMNANPC1RAB9AGOT1 | |
| SCHEMBL21432138 | 0.75 | GABRA1 (0.42) | SMN1; SMN2ALDH1A1CYP1A2KMT2A | |
| SCHEMBL17295055 | 0.74 | NPC1 (0.53) | KDM4ELMNANPC1RAB9AGOT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160378-B | Red-light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-115010765-B | Red-light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2024-08-20 | — | — | CN | claimed |
| CN-115252814-A | Cyclodextrin-metal organic framework composition and preparation method thereof | 中国科学院上海药物研究所 | 2022-11-01 | — | — | CN | claimed |
| CN-115160378-A | Red light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2022-10-11 | — | — | CN | claimed |
| CN-113461739-B | Red light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2022-09-27 | — | — | CN | claimed |
| CN-115010765-A | Red light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2022-09-06 | — | — | CN | claimed |
| CN-113461739-A | Red light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2021-10-01 | — | — | CN | claimed |
| US-7531653-B2 | Manufacture of pure hydralazine salts | NAVINTA LLC (US) | 2009-05-12 | — | — | US | claimed |
| CN-101245063-A | Method for synthesizing cinchona alkaloids microwave radiation non-solvent | FOURTH MILITARY MEDICAL UNIV (CN) | 2008-08-20 | — | — | CN | claimed |
| US-20070129546-A1 | Manufacture of pure hydralazine salts | NAVINTA LLC | 2007-06-07 | — | — | US | claimed |
| US-7220858-B2 | Synthesis of hydrazine and chlorinated derivatives of bicyclic pyridazines | BARBEAU PHARMA, INC. (US) | 2007-05-22 | — | — | US | claimed |
| US-20050137397-A1 | Synthesis of hydrazine derivatives of pyridazine | BIONICHE TEORANTA | 2005-06-23 | — | — | US | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| JP-3246292-A | — | — | None | — | — | JP | disclosed |
| JP-11222486-A | — | — | None | — | — | JP | disclosed |
| JP-58004138-A | — | — | None | — | — | JP | disclosed |
| US-4466965-A | ANTIARRMYTHMIA AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| EP-0114878-A1 | PHTHALAZINE SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES, COMPOSITIONS AND USE. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-08-08 | — | — | EP | disclosed |
| WO-1984000489-A1 | HETEROARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES, COMPOSITIONS AND USE | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-02-16 | — | — | WO | disclosed |
| JP-S584138-A | PHOTOSENSITIVE RESIN COMPOSITION | HITACHI CHEM CO LTD | 1983-01-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137397-A1 | Synthesis of hydrazine derivatives of pyridazine | DHPS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HPD | KDM4E 1250/4885LMNA 2909/4885NPC1 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.