SCHEMBL14768872

SCHEMBL14768872

SC1=Nc2cc3ccccc3cc2C1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
PKM P14618 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NQO2 P16083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105679 0.78 KMT2A (0.38) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL25633341 0.76 NOS3 (0.42) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL9924581 0.74 NOS3 (0.43) MEN1KMT2ANPC1CYP3A4CYP2D6
SCHEMBL13254454 0.73 ALDH1A1 (0.42) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL12793863 0.72 MAPT (0.34) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL26747098 0.69 NQO1 (0.39) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL13086560 0.68 DRD2 (0.41) KDM4ECYP3A4CYP2C9CYP2C19
SCHEMBL17739570 0.68 METAP1 (0.34) KMT2AKDM4ENPC1MAPTPKM
SCHEMBL7914941 0.67 MEN1 (0.52) MEN1KMT2AKDM4ENPC1TP53
SCHEMBL1808685 0.67 MEN1 (0.52) MEN1KMT2AKDM4ENPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181628-B2 Coating/sealant systems, aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-11-10 US disclosed
US-20150287953-A1 TRANSPARENT ELECTRODE, ELECTRONIC DEVICE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Konica Minolta, Inc. (JP) 2015-10-08 US disclosed
US-9029437-B2 Coating/sealant systems, aqueous resinous dispersions, methods for making aqueous resinous dispersions, and methods of electrocoating PRC-DESOTO INTERNATIONAL, INC. (US) 2015-05-12 US disclosed
US-20130065985-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, METHODS FOR MAKING AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed
US-20130065057-A1 COATING/SEALANT SYSTEMS, AQUEOUS RESINOUS DISPERSIONS, AND METHODS OF ELECTROCOATING PRC-DESOTO INTERNATIONAL, INC. (US) 2013-03-14 US disclosed