SCHEMBL9924581

SCHEMBL9924581

SC1=Nc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
NOS2 P35228 1/20 0.43
TRPA1 O75762 3/20 0.42
SIGMAR1 Q99720 1/20 0.41
HRH4 Q9H3N8 1/20 0.40
NPC1 O15118 2/20 0.37
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 1/20 0.37
ACHE P22303 5/20 0.36
BCHE P06276 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CYP2D6 P10635 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzene SCHEMBL7210466 0.81 ALDH1A1 (0.50) NOS3NOS1NOS2ALDH1A1RAB9A
SCHEMBL14153565 0.79 NOS3 (0.57) NOS3NOS1NOS2SIGMAR1NPC1
SCHEMBL12066839 0.76 NOS3 (0.48) NOS3NOS1NOS2SIGMAR1NPC1
SCHEMBL5021700 0.75 NOS3 (0.46) NOS3NOS1NOS2TRPA1SIGMAR1
SCHEMBL14768872 0.74 MEN1 (0.36) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL9674946 0.74 NOS3 (0.42) NOS3NOS1NOS2TRPA1SIGMAR1
SCHEMBL47849 0.71 NOS3 (0.43) NOS3NOS1NOS2TRPA1SIGMAR1
SCHEMBL4183978 0.71 NOS3 (0.43) NOS3NOS1NOS2TRPA1SIGMAR1
SCHEMBL11780213 0.71 NOS3 (0.43) NOS3NOS1NOS2TRPA1SIGMAR1
SCHEMBL35438 0.71 NOS3 (0.48) NOS3NOS1NOS2TRPA1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208200-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING PRINTING PLATE FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed
US-12018177-B2 Polymeric agents and compositions for inhibiting corrosion THE BOEING COMPANY (US) 2024-06-25 US disclosed
US-11874602-B2 Lithographic printing plate precursor, method for preparing lithographic printing plate, and lithographic printing method FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
US-11844275-B2 Organic compound, organic light emitting diode and organic light emitting deice including the organic compound LG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11803124-B2 Planographic printing plate precursor, method of preparing planographic printing plate, and planographic printing method FUJIFILM CORPORATION (JP) 2023-10-31 US disclosed
US-11787973-B2 Sliding member and method for manufacturing same ASAHI FR R&D CO., LTD. (JP) 2023-10-17 US disclosed
US-11746245-B2 Soluble corrosion resistant sol-gel THE BOEING COMPANY (US) 2023-09-05 US disclosed
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-07-27 US disclosed
US-20230226814-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230212374-A1 RUBBER COMPOSITION FOR GOLF BALL, AND GOLF BALL BRIDGESTONE SPORTS CO., LTD. (JP) 2023-07-06 US disclosed
US-20110143211-A1 ELECTROCHEMICAL DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-06-16 US disclosed
US-20110129632-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION HAVING AN IMPROVED RELEASE BEHAVIOR TESA SE (DE) 2011-06-02 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20110045412-A1 PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed
US-20110028518-A1 DEXLANSOPRAZOLE PROCESS AND POLYMORPHS DR. REDDY'S LABORATORIES LTD. (IN) 2011-02-03 US disclosed
US-20110019265-A1 DISPLAY ELEMENT AND METHOD OF FORMING POROUS LAYER IN DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-27 US disclosed
US-20110013261-A1 ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-20 US disclosed
US-7872059-B2 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-20110003241-A1 RESIN, PIGMENT DISPERSION, COLORED CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
EP-1341035-B1 Silver halide color photographic light-sensitive material FUJIFILM CORP (JP) 2007-12-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF CRBN, CRKL, ERBB3 NOS3 3895/4885NOS1 4243/4885NOS2 4025/4885
US-11844275-B2 Organic compound, organic light emitting diode and organic light emitting deice including the organic compound OCIAD1, OCIAD2, ORC3 NOS3 2268/4885NOS1 3117/4885NOS2 3231/4885
US-12018177-B2 Polymeric agents and compositions for inhibiting corrosion MGMT, MPO, MAOA NOS3 443/4885NOS1 411/4885NOS2 332/4885
US-20110028518-A1 DEXLANSOPRAZOLE PROCESS AND POLYMORPHS CYP2C19, CYP3A4, CYP2D6 NOS3 2644/4885NOS1 2975/4885NOS2 2907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.