SCHEMBL14769374

SCHEMBL14769374

C[N+](C)(CN)CS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
SLC6A6 P31641 1/20 0.38
CYP2C19 P33261 1/20 0.38
BLM P54132 1/20 0.38
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14964807 0.83 PTGS1 (0.32) LMNASLC6A6CYP2C19BLM
SCHEMBL14769414 0.80 LMNA (0.40) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL172218 0.76 BBOX1 (0.38)
SCHEMBL13133621 0.72 DNM1 (0.37)
SCHEMBL17058679 0.72 DNM1 (0.38) LMNABLM
SCHEMBL25137107 0.72 APP (0.50) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL12034970 0.71
SCHEMBL18026507 0.70
Hydrogen Sulfide SCHEMBL28060373 0.66
Tetramethylammonium Ion SCHEMBL330775 0.64 CA5A (0.36) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4183773-A1 ZWITTERIONIC REAGENTS Siemens Healthcare Diagnostics Inc. (US) 2023-05-24 EP disclosed
US-9487480-B2 Zwitterionic reagents SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2016-11-08 US disclosed
US-20160274094-A1 ZWITTERIONIC REAGENTS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2016-09-22 US disclosed
US-9353056-B2 2016-05-31 US disclosed
US-20130065325-A1 ZWITTERIONIC REAGENTS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065325-A1 ZWITTERIONIC REAGENTS BTD, HLCS, WIZ LMNA 699/4885SLC6A6 2243/4885CYP2C19 4811/4885
US-20160274094-A1 ZWITTERIONIC REAGENTS BTD, HLCS, WIZ LMNA 699/4885SLC6A6 2243/4885CYP2C19 4811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.