Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 3/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14964807 | 0.70 | PTGS1 (0.32) | BLMLMNACYP2C19PTGS1 | |
| SCHEMBL24433087 | 0.69 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL18085805 | 0.68 | MGLL (0.41) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL155453 | 0.66 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL172218 | 0.64 | BBOX1 (0.38) | — | |
| SCHEMBL63993 | 0.63 | MGLL (0.42) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL17539691 | 0.63 | MGLL (0.39) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL15809670 | 0.63 | MGLL (0.60) | MGLLALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL14769374 | 0.62 | LMNA (0.38) | BLMLMNACYP2C19 | |
| SCHEMBL29893970 | 0.60 | MGLL (0.45) | MGLLALDH1A1BLMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183773-A1 | ZWITTERIONIC REAGENTS | Siemens Healthcare Diagnostics Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| US-9487480-B2 | Zwitterionic reagents | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9353056-B2 | — | — | 2016-05-31 | — | — | US | disclosed |
| US-20130065325-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065325-A1 | ZWITTERIONIC REAGENTS | BTD, HLCS, WIZ | MGLL 4058/4885ALDH1A1 4381/4885BLM 2999/4885 |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | BTD, HLCS, WIZ | MGLL 4058/4885ALDH1A1 4381/4885BLM 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.