SCHEMBL14770324

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14770325	0.86	LMNA (0.35)	ALDH1A1TP53RECQLCYP17A1CYP19A1
	SCHEMBL14770321	0.85	ALDH1A1 (0.35)	ALDH1A1TP53GAAL3MBTL1LMNA
	SCHEMBL14770314	0.82	NPSR1 (0.37)	ALDH1A1NPSR1
	SCHEMBL14770347	0.79	NPSR1 (0.40)	ALDH1A1SMN1; SMN2L3MBTL1NPSR1MEN1
	SCHEMBL14760516	0.78	NPSR1 (0.40)	ALDH1A1SMN1; SMN2L3MBTL1NPSR1MEN1
	SCHEMBL14760530	0.78	ALDH1A1 (0.34)	ALDH1A1TP53HTTGAAL3MBTL1
	SCHEMBL14770349	0.77	NPSR1 (0.38)	ALDH1A1L3MBTL1NPSR1MEN1KMT2A
	SCHEMBL22043550	0.76	NPSR1 (0.45)	ALDH1A1HTTGAAL3MBTL1LMNA
	SCHEMBL14760564	0.76	NPSR1 (0.37)	ALDH1A1NPSR1
	SCHEMBL24268504	0.76	NPSR1 (0.41)	ALDH1A1L3MBTL1NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.