Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 12/20 | 0.60 |
| ▸ | RXRA | P19793 | 10/20 | 0.60 |
| ▸ | RXRB | P28702 | 9/20 | 0.60 |
| ▸ | RXRG | P48443 | 6/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 3/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | C5 | P01031 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867495 | 0.85 | NR4A2 (0.73) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL13391166 | 0.84 | NR4A2 (0.58) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL13653143 | 0.82 | NR4A2 (0.65) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL28240013 | 0.81 | NR4A2 (0.50) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL14773995 | 0.79 | NR4A2 (0.67) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL13653142 | 0.79 | NR4A2 (0.69) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7492453 | 0.79 | NR4A2 (0.66) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL11719710 | 0.79 | NR4A2 (0.65) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL16744267 | 0.79 | RXRA (0.72) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL2760386 | 0.78 | NR4A2 (0.63) | NR4A2RXRARXRBRXRGNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160106712-A1 | FATTY ACID COX INHIBITOR DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS INC (US) | 2016-04-21 | — | — | US | disclosed |
| US-9216224-B2 | Fatty acid COX inhibitor derivatives and their uses | CATABASIS PHARMACEUTICALS, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| US-20150148306-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | KANDULA MAHESH (IN) | 2015-05-28 | — | — | US | disclosed |
| US-20140315786-A1 | USE OF INTRACELLULAR ENZYMES FOR THE RELEASE OF COVALENTLY LINKED BIOACTIVES | CATABASIS PHARMACEUTICALS, INC. (US) | 2014-10-23 | — | — | US | disclosed |
| US-20130065934-A1 | FATTY ACID COX INHIBITOR DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160106712-A1 | FATTY ACID COX INHIBITOR DERIVATIVES AND THEIR USES | PTGES, PTGES2, ALOX5 | NR4A2 1362/4885RXRA 356/4885RXRB 468/4885 |
| US-20150148306-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION | IAPP, TTR, GPR119 | NR4A2 568/4885RXRA 260/4885RXRB 343/4885 |
| US-20140315786-A1 | USE OF INTRACELLULAR ENZYMES FOR THE RELEASE OF COVALENTLY LINKED BIOACTIVES | GAA, GUSB, ACER2 | NR4A2 4351/4885RXRA 3556/4885RXRB 2871/4885 |
| US-20130065934-A1 | FATTY ACID COX INHIBITOR DERIVATIVES AND THEIR USES | PTGES, ALOX5, PTGES2 | NR4A2 1311/4885RXRA 347/4885RXRB 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.