Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | COMT | P21964 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770708 | 0.87 | MLKL (0.42) | AMY1AAPPCYP3A4GRIN2DGRIN3B | |
| SCHEMBL14770628 | 0.85 | NUDT1 (0.37) | AMY1ACOMTCYP2C19CYP1A2CYP2E1 | |
| SCHEMBL14770642 | 0.81 | PARP1 (0.40) | GAA | |
| SCHEMBL14770630 | 0.77 | AMY1A (0.42) | AMY1ACOMTCYP2C19CYP1A2CYP2E1 | |
| SCHEMBL14770550 | 0.76 | FLT3 (0.40) | AMY1ACYP2C19CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL14770492 | 0.73 | AMY1A (0.41) | AMY1ACOMTPTGESALOX5LTC4S | |
| SCHEMBL14770674 | 0.72 | SMN1; SMN2 (0.56) | PTGESALOX5LTC4SGAA | |
| SCHEMBL14770549 | 0.72 | ALDH1A1 (0.42) | COMTCYP2C19CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL23676458 | 0.72 | HSD17B10 (0.41) | AMY1ACYP2C19CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL14770519 | 0.72 | MAPK1 (0.38) | COMTCYP2C19CYP1A2CYP2E1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096531-B2 | Fused imidazole derivative | TOA EIYO LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | CACNA1E, CACNA1G, CACNA1A | AMY1A 4661/4885APP 2799/4885COMT 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.