Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 4/20 | 0.45 |
| ▸ | CDK1 | P06493 | 4/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065646 | 0.86 | PDE2A (0.41) | RIPK1PDE2A | |
| SCHEMBL14770516 | 0.81 | GAA (0.46) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL14770686 | 0.81 | MLKL (0.60) | MLKLNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL14770730 | 0.76 | MLKL (0.44) | MLKLNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16447860 | 0.73 | ROCK2 (0.48) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL14770731 | 0.73 | MEN1 (0.49) | MLKLNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23181665 | 0.72 | ALDH1A1 (0.35) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL12066053 | 0.72 | MLKL (0.41) | MLKLNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1106425 | 0.72 | HSD17B10 (0.46) | CCNB2CDK1CCNB1CCNB3RIPK1 | |
| SCHEMBL14770521 | 0.70 | NPC1 (0.42) | MLKLNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096531-B2 | Fused imidazole derivative | TOA EIYO LTD. (JP) | 2015-08-04 | — | — | US | disclosed |
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA EIYO LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065896-A1 | FUSED IMIDAZOLE DERIVATIVE | CACNA1E, CACNA1G, CACNA1A | CCNB2 2298/4885CDK1 597/4885CCNB1 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.