Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775936 | 0.82 | FBP1 (0.37) | L3MBTL1TDP1GAAS100A4POLB | |
| SCHEMBL12082320 | 0.73 | CDK2 (0.52) | TDP1POLBMAPK1TSHRAKR1C3 | |
| SCHEMBL11313940 | 0.73 | TDP1 (0.42) | L3MBTL1TDP1S100A4POLBTSHR | |
| SCHEMBL2837833 | 0.73 | ALDH1A1 (0.52) | L3MBTL1TDP1GAAS100A4POLB | |
| SCHEMBL27907819 | 0.73 | ALDH1A1 (0.50) | L3MBTL1TDP1GAAPOLBMAPK1 | |
| SCHEMBL12082250 | 0.72 | PKM (0.53) | L3MBTL1TDP1POLBMAPK1ALDH1A1 | |
| SCHEMBL9735780 | 0.72 | DBH (0.49) | L3MBTL1TDP1GAAPOLBMAPK1 | |
| SCHEMBL28360177 | 0.72 | GAA (0.41) | TDP1GAAPOLBMAPK1TSHR | |
| SCHEMBL8402833 | 0.72 | GAA (0.45) | GAAMAPK1HNF4AALDH1A1LMNA | |
| SCHEMBL1658633 | 0.72 | LMNA (0.48) | TDP1GAAPOLBMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |