Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775871 | 0.83 | LMNA (0.41) | ALDH1A1POLBL3MBTL1GAAALOX5 | |
| SCHEMBL14775748 | 0.82 | L3MBTL1 (0.42) | ALDH1A1S100A4MAPK1POLBTDP1 | |
| SCHEMBL14775713 | 0.79 | PKM (0.32) | FBP1ALDH1A1GAA | |
| SCHEMBL9489749 | 0.78 | IMPDH2 (0.38) | FBP1S100A4POLBTDP1L3MBTL1 | |
| SCHEMBL14775910 | 0.77 | FTO (0.35) | ALDH1A1 | |
| SCHEMBL27926028 | 0.74 | MAPK1 (0.41) | ALDH1A1MAPK1POLBVCAM1GAA | |
| SCHEMBL28079652 | 0.73 | MAPK1 (0.48) | FBP1ALDH1A1MAPK1POLBTDP1 | |
| SCHEMBL5590503 | 0.73 | LDHA (0.36) | FBP1S100A4TDP1L3MBTL1 | |
| SCHEMBL27907899 | 0.72 | MAPK1 (0.40) | ALDH1A1MAPK1POLBVCAM1AKR1C3 | |
| SCHEMBL27908005 | 0.72 | CYP19A1 (0.40) | ALDH1A1MAPK1POLBVCAM1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |