Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874417 | 0.98 | HTT (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3483124 | 0.96 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL19131086 | 0.96 | DNM1 (0.53) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3482684 | 0.92 | HTT (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921161 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921103 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921129 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921123 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921081 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL16921097 | 0.89 | LPAR1 (0.47) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981165-B2 | Process for lightening keratin materials using an anhydrous composition comprising at least one fatty substance and at least one alkaline agent, and at least one oxidizing composition | L'OREAL S.A. (FR) | 2011-07-19 | — | — | US | disclosed |
| US-7914591-B2 | Process for the lightening dyeing of keratin materials using at least one anhydrous dyeing composition comprising at least one alkaline agent and at least one oxidizing composition | L'OREAL S.A. (FR) | 2011-03-29 | — | — | US | disclosed |
| US-20100186177-A1 | PROCESS FOR THE LIGHTENING DYEING OF KERATIN MATERIALS USING AT LEAST ONE ANHYDROUS DYEING COMPOSITION COMPRISING AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE OXIDIZING COMPOSITION | L'OREAL S.A. (FR) | 2010-07-29 | — | — | US | disclosed |
| US-20100178263-A1 | PROCESS FOR LIGHTENING KERATIN MATERIALS USING AN ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ALKALINE AGENT, AND AT LEAST ONE OXIDIZING COMPOSITION | L'OREAL S.A. (FR) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100186177-A1 | PROCESS FOR THE LIGHTENING DYEING OF KERATIN MATERIALS USING AT LEAST ONE ANHYDROUS DYEING COMPOSITION COMPRISING AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE OXIDIZING COMPOSITION | KRT18, ADH1B, AKR1A1 | HTT 4099/4885MEN1 4504/4885THRB 4335/4885 |
| US-20100178263-A1 | PROCESS FOR LIGHTENING KERATIN MATERIALS USING AN ANHYDROUS COMPOSITION COMPRISING AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ALKALINE AGENT, AND AT LEAST ONE OXIDIZING COMPOSITION | KRT18, AKR1B10, FABP4 | HTT 4335/4885MEN1 4809/4885THRB 4664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.