Sugi Predict

Sugi Predict / Compounds / SCHEMBL3482684

SCHEMBL3482684

SCHEMBL3482684

CCCCCCCCCCCCCCCCCCOCCOC(CC)CCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ THRB P10828 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ DNM1 Q05193 1/20 0.46
▸ LPAR1 Q92633 6/20 0.42
▸ LPAR3 Q9UBY5 6/20 0.42
▸ LPAR2 Q9HBW0 3/20 0.42
▸ USP2 O75604 1/20 0.39
▸ TLR2 O60603 3/20 0.39
▸ PRKD3 O94806 1/20 0.38
▸ PRKCG P05129 1/20 0.38
▸ PRKCB P05771 1/20 0.38
▸ PRKCA P17252 1/20 0.38
▸ PRKCH P24723 1/20 0.38
▸ PRKCI P41743 1/20 0.38
▸ PRKCE Q02156 1/20 0.38
▸ PRKCQ Q04759 1/20 0.38
▸ PRKCZ Q05513 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6009964 0.96 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL1478563 0.92 HTT (0.52) HTTMEN1THRBKMT2AMAPT
SCHEMBL874417 0.90 HTT (0.50) HTTMEN1THRBKMT2AMAPT
SCHEMBL3483124 0.89 HTT (0.48) HTTMEN1THRBKMT2AMAPT
SCHEMBL19131086 0.88 DNM1 (0.53) HTTMEN1THRBKMT2AMAPT
SCHEMBL23017083 0.88 DNM1 (0.57) DNM1LPAR1LPAR3LPAR2TLR2
SCHEMBL13292250 0.88 DNM1 (0.57) DNM1LPAR1LPAR3LPAR2TLR2
SCHEMBL25258976 0.88 DNM1 (0.57) DNM1LPAR1LPAR3LPAR2TLR2
SCHEMBL7156427 0.88 DNM1 (0.57) DNM1LPAR1LPAR3LPAR2TLR2
SCHEMBL28360383 0.88 DNM1 (0.57) DNM1LPAR1LPAR3LPAR2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020216641-A1 A HAIR WAX COMPOSITION BEIERSDORF AG (DE) 2020-10-29 — — WO claimed
US-9655824-B2 Use of diphenylmethane derivatives as tyrosinase inhibitors SYMRISE AG (DE) 2017-05-23 — — US disclosed
US-9526687-B2 Polymers based on sulfonic acids, amides and special cross-linking agents CLARIANT INTERNATIONAL LTD. (CH) 2016-12-27 — — US disclosed
US-20140086854-A1 Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents CLARIANT FINANCE (BVI) LIMITED (VG) 2014-03-27 — — US disclosed
US-8409552-B2 Anthranillic acid amides and derivatives thereof as cosmetic and pharmaceutical active compounds SYMRISE AG (DE) 2013-04-02 — — US disclosed
US-20120315233-A1 ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS SYMRISE AG (DE) 2012-12-13 — — US disclosed
US-8241681-B2 Synergistic mixtures of bisabolol and ginger extract SYMRISE AG (DE) 2012-08-14 — — US disclosed
US-8203016-B2 Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents SYMRISE AG (DE) 2012-06-19 — — US disclosed
US-20100216892-A1 Use of synergistically active 1,2-alkanediol mixtures as skin moisture-regulating compositions SYMRISE GMBH & CO. KG (DE) 2010-08-26 — — US disclosed
US-20090220625-A1 SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT SYMRISE AG (DE) 2009-09-03 — — US disclosed
US-7582681-B2 Synergistic mixtures of 1,2-alkane diols SYMRISE GMBH & CO. KG (DE) 2009-09-01 — — US disclosed
EP-1937366-A1 SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT Symrise GmbH & Co. KG (DE) 2008-07-02 — — EP disclosed
US-7282197-B2 Antiperspirant gel BEIERSDORF AG (DE) 2007-10-16 — — US disclosed
EP-1835843-A1 USE OF SYNERGISTICALLY ACTIVE 1,2-ALKANEDIOL MIXTURES AS SKIN MOISTURE-REGULATING COMPOSITIONS Symrise GmbH & Co. KG (DE) 2007-09-26 — — EP disclosed
US-20070098655-A1 Use of diphenylmethane derivatives as tyrosinase inhibitors SYMRISE AG (DE) 2007-05-03 — — US disclosed
WO-2007042472-A1 SYNERGISTIC MIXTURES OF BISABOLOL AND GINGER EXTRACT SYMRISE GMBH & CO. KG (DE) 2007-04-19 — — WO disclosed
WO-2006069953-A1 USE OF SYNERGISTICALLY ACTIVE 1, 2-ALKANEDIOL MIXTURES AS SKIN MOISTURE-REGULATING COMPOSITIONS SYMRISE GMBH & CO. KG (DE) 2006-07-06 — — WO disclosed
US-20060089413-A1 Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents SYMRISE GMBH & CO. KG (DE) 2006-04-27 — — US disclosed
US-20050222276-A1 Synergistic mixtures of 1,2-alkane diols SYMRISE AG (DE) 2005-10-06 — — US disclosed
US-20050048013-A1 Antiperspirant gel BEIERSDORF AG (DE) 2005-03-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222276-A1 Synergistic mixtures of 1,2-alkane diols BAK1, ERG28, ADH1A HTT 4778/4885MEN1 1326/4885THRB 2742/4885
US-20060089413-A1 Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents HRH1, CMA1, HRH2 HTT 2533/4885MEN1 1771/4885THRB 4403/4885
US-20140086854-A1 Polymers Based On Sulfonic Acids, Amides And Special Cross-Linking Agents ACMSD, SRM, TAS1R1 HTT 884/4885MEN1 2109/4885THRB 4471/4885
US-20120315233-A1 ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS CMA1, TPSAB1, HRH1 HTT 2046/4885MEN1 1612/4885THRB 4482/4885
US-20070098655-A1 Use of diphenylmethane derivatives as tyrosinase inhibitors TYR, DPM1, DDT HTT 2307/4885MEN1 2900/4885THRB 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.