Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788325 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL14788388 | 0.86 | GPX4 (0.49) | C5AR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29864762 | 0.86 | GPX4 (0.49) | C5AR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12696372 | 0.78 | ATM (0.45) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL14788496 | 0.77 | GPX4 (0.49) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL14788390 | 0.76 | GPX4 (0.54) | C5AR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29172532 | 0.75 | GPX4 (0.43) | C5AR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12696355 | 0.74 | C5AR1 (0.42) | C5AR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12696373 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL11443834 | 0.67 | CYP3A4 (0.64) | ALDH1A1MEN1KMT2AHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | RELA, NFE2, NCOA1 | C5AR1 1864/4885ALDH1A1 1558/4885MAPT 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.