SCHEMBL1479792

SCHEMBL1479792

Cc1ccccc1-c1cc2c(cc1C(C)(C)C)-c1cc(C(C)(C)C)c(-c3ccccc3C)cc1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
ALDH1A1 P00352 4/20 0.47
CASP3 P42574 3/20 0.47
SENP7 Q9BQF6 3/20 0.47
SENP6 Q9GZR1 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
SENP8 Q96LD8 2/20 0.47
PLA2G1B P04054 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
ELANE P08246 2/20 0.43
SMN1; SMN2 Q16637 5/20 0.41
LMNA P02545 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480126 0.90 ALDH1A1 (0.67) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1480253 0.81 ELANE (0.46) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1479840 0.80 NPC1 (0.45) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL4567546 0.79 RAB9A (0.64) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1482936 0.79 S100A4 (0.43) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL16411547 0.77 GABRA1 (0.36) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1480667 0.76 GABRA1 (0.35) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1481069 0.76 NPC1 (0.44) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL27960858 0.76 GABRA1 (0.35) NPC1RAB9AALDH1A1CASP3SENP7
SCHEMBL1480249 0.74 NPC1 (0.54) NPC1RAB9AALDH1A1CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed